Title: A Prospective Study on the Incidence of Malignancy in Multi-Nodular Goitre at a Tertiary Care Academic Hospital
Authors: Bharani Rajkumar, Inpharasun SA, Kannan I, Jeyachandra Mohan A
DOI: https://dx.doi.org/10.18535/jmscr/v5i3.33
Abstract
Multinodular goiter (MNG) is a clinicopathological entity characterized by an increased volume of the thyroid gland with formation of nodules. In general, MNG has been considered to be at low risk for malignancy as compared to a solitary nodule thyroid. There is a worldwide increase in the incidence of thyroid carcinoma. The prospective observational study was carried out in the Department of Surgery at the Tagore Medical College and Hospital, Chennai, India from January 2016 to December 2016. Selected patients were offered surgery (total thyroidectomy) as the treatment. After the surgery, all the thyroid specimens were sent for a histopathological evaluation. In the present study, we have 25% incidence of carcinoma, for the cases operated for MNG with no etiological relation to any risk factor. Hence it is imperative for MNG cases to undergo follow up for diagnosis of malignancy.
Keywords: Thyroid nodules, Multi-nodular goiter (MNG), thyroid carcinoma, papillary carcinoma, micro papillary carcinoma, follicular carcinoma.
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