Title: Serum Magnesium Levels in Type 2 Diabetes Mellitus and its Association with the Microvascular Complications

Authors: Dr Sajal Kamat (MBBS MD), Dr Dnyanesh Morkar (MBBS, MD, DNB, FGSI),  Dr Siddharth Madnani (MBBS MD)

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i2.137

Abstract

Background and Objectives: Hypomagnesemia has been associated with type 2 diabetic mellitus. This study aimed to evaluate serum magnesium levels in patients with type 2 DM and study its association with the microvascular complications.

Methodology: The present one year hospital based cross-sectional study was done on 150 patients with type 2 diabetes mellitus from January 2014 to December 2014 in Department of Medicine, KLES Dr. Prabhakar Kore Hospital and Medical Research Centre, Belgaum. Serum magnesium levels were assessed in all the diabetic patients and they were also tested for presence of microvascular complications.

Results: In the present study majority of the patients (71.33%) were males and male to female ratio was 2.48:1. The commonest age group was > 60 years (50%). The duration of diabetes in 45.33% of the patients was between 6 to 10 years. HbA1c levels were ≥8.5% in 51.33% of the patients. Serum magnesium levels were < 1.8 mg/dL in 41.33% of the patients. Microvascular complications were present in 54.67% of the patients and diabetic retinopathy was present in 32%. Diabetic nephropathy and diabetic peripheral neuropathy were seen in 36% of the patients each. Also association was found between serum magnesium levels glycaemic control and duration of diabetes (p<0.050).

Conclusion: Hypomagnesemia is widely prevalent in patients with type 2 diabetes mellitus and a major risk factor for the development microvascular complications

Keywords : Hypomagnesemia; Diabeticnephropathy; Diabeticneuropathy; Diabeticretinopathy; Microva-scular complications ; Type 2 Diabetes Mellitus.

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