Title: Role of Fetal MRI in detection of CNS anomalies

Authors: Dr Karanbir S Bajwa, Dr Sanjay B Shahu, Dr Avinash P Dhok, Dr Sushupti M Chaukhande,  Dr Purva M Agarwal,  Dr Gurnihal S Chawla

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i2.116

Abstract

Context: Congenital malformation is a stimulating problem for research. The commonest of these are CNS anomalies (1).  The abnormalities detected on Ultrasound may at times be very subtle or inconclusive. In such cases, several studies have shown that MRI is a helpful modality.

Aims: 1.To establish role of MRI in detection and evaluation of CNS anomalies.

2. To assess whether fetal MRI provides additional information to findings detected on USG.

Settings and Design: Cross sectional study

Methods and Material: All pregnant women referred to our department within 2 years, were examined by USG. 36 patients with fetal CNS anomalies detected on USG were subsequently examined by MRI and results were analyzed statistically.

Statistical Analysis Used: Quantitative and Qualitative data are presented with the help of Mean and Standard deviation& frequency and percentage table respectively. Association among study groups is assessed by Fisher test, student ‘t’ test and Chi-Square test. ‘p’ value less than 0.05 is taken as significant.

Results: Ultrasound detected and suspected anomalies in 36 cases of CNS, which were subsequently confirmed or further characterized with some additional information obtained or were concordant on MRI. There were also some cases that turned out to be normal on MRI and some where the MRI findings were totally discordant with the USG findings.

Conclusions: MRI is superior to USG in diagnosing CNS anomalies of the fetus. MRI can add additional diagnostic information to sonography in fetuses for which prenatal intervention is being considered.

Keywords: CNS anomalies, MRI, USG.

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