Title: Study of Epidemiology, Morphological and Histopathological Changes of Stomach and Kidneys in Poisonous Snake Bite

Authors: Dr Alakesh Halder, Dr Niloy Kumar Das, Dr Tumpa Mandal, Dr Ashok Kumar Samanta

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i2.113

Abstract

Snakes have always managed to grab human attention and have been an object of fear since historic civilisation. Deaths due to poisonous snakebite are a significant health related problem especially the rural area in tropical countries. We investigated the renal and stomach changes at autopsy and histology of poisonous snake bites .Our study included the macroscopical and microscopical examination of stomach and kidneys of 53 cases of poisonous snake bite victims  who were admitted to Nil Ratan Sircar Medical College, Kolkata as a result of development of acute renal failure following envenomation.In 100% cases vasculotoxic snake bite resulted in kidney congestion along with different types of hemorrhage. Only 44% cases of neurotoxic snake bite victims had kidney congestion in absence of any hemorrhage. vasculotoxic snake bite cases tubular necrosis was the commonest findings 89% followed by interstitial edema and glomerulonephritis  both in 57% cases. Related to stomach findings out of 9 neurotoxic snake bite only 33% cases had congestion, 67% had nonspecific changes where as in all cases of vasculotoxic snake bite had congestion,36% cases had patchy submucosal hemorrhage and 39% cases had diffuse submucosal hemorrhage.

Keywords: Snake Bite, Congestion, Sub mucosal hemorrhage, Tubular Necrosis, Autopsy

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