Title: Necrotizing Soft Tissue Infections

Authors: K. Anand Goud, C.Naga Raghavendra Reddy

 DOI:  https://dx.doi.org/10.18535/jmscr/v5i2.49

Abstract

Necrotizing soft tissue infections (NSTIs) rank among the more difficult disease processes encountered by physicians and surgeons, are aggressive infections that can result in severe disability or death. This study consist of 50 patients with necrotizing soft tissue infections were admitted to Mamata general hospital  in Khammam, Telangana state during last 5 years period.  Patients of both sexes aged between 20-70 years are included in this study.  NSTI is more prevalent in female and also common in old age patients suffering with diabetes. Risk factors include chronic disease like diabetes, lower extremity venous insufficiency, old age, obesity/ malnutrition, immunocompromised, alcoholism, drug abuse, pregnancy. NSTIs most commonly seen in the perineum, extremities, genitalia, with fewer arising on the chest or the abdomen. Most of infections are associated with bacterial infections and commonly isolated organism is streptococcus. The average time from initiation of symptoms to hospital admission was 5 days. Wound closure was begun as soon as the infection was controlled, and often was started early-2 to 4 days after initial debridement. Forty patients successfully achieved wound closure during initial hospitalization, an average of 27 days after initial debridement and ten patients were discharged from the hospital with open wounds, left to close by secondary intention. Early diagnosis, hospital admission and surgical debridement helps in treatment of disease and decreases the mortality rates.

Keywords- Necrotizing, soft tissue, infections, risk factors, fasciitis, mortality.

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