Title: A Comparative Analysis of Mean Platelet Volume and Other Platelet Indices in Patient of Acute Myocardial Infarction with Healthy Control- Prospective Study
Authors: Dr P.S Pipliwal, Dr Rohit Mathur, Dr Anjana Mathur, Dr Gajraj Singh
DOI: https://dx.doi.org/10.18535/jmscr/v5i2.31
Abstract
Background: Coronary artery disease caused by atherosclerosis and its complications. Platelets has important role in atherosclerosis and thrombus formation. Mean platelet volume is affected by inflammation and there is little data regarding its relation with coronary artery disease.
Aims & Objective: To study the mean platelet volume and other platelet indices in patient of acute myocardial infarction with healthy controls.
Material and Methods: This study was a comparative analysis done in the department of medicine at SMS medical college Rajasthan. 60 subjects with acute myocardial infarction diagnosed on the basis of symptoms, ECG changes and Troponin I/T was compared with 60 healthy individuals of same age and sex. MPV and other platelet indices done within 6 hours of symptoms before administration of anticoagulant. Inclusion and exclusion criteria was applied in both groups
Results: It was observed that cases has lower platelet count, higher MPV higher PDW higher P-LCR, low PCT levels as compared to healthy controls
Conclusion: Measurement of MPV may be of some benefit in detecting those patients at higher risk for CAD
Keywords: Acute myocardial infarction, MPV, coronary artery disease.
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