Title: A Study of Clonidine and Dexmedetomidine as Adjuvant to Epidural Levobupivacaine for Post Operative Analgesia in Infraumbilical Surgeries
Authors: Dr Narayan Acharya, Dr Daityari Routray
DOI: https://dx.doi.org/10.18535/jmscr/v5i2.10
Abstract
Background: Epidural analgesia with adjuvant is the popular method for intra and postoperative pain relief but search for ideal adjuvant for prolonging the duration of postoperative analgesia without any side effect goes on.
Aim: This study was conducted to study the onset, extent and duration of sensory and motor block and side effects of clonidine or dexmedetomidine when used as an adjuvant in epidural levobupivacaine.
Materials and Methods: 80 patients of ASA status I and II, posted for infraumbilical surgery were randomly allocated into two groups of 40 each. Group I group patients received 18 ml of 0.5% levobupivacaine and clonidine 2mcg/kg in epidural route and Group II group patients received 18 ml of 0.5% levobupivacaine and dexmedetomidine 1.5mcg/kg in epidural route. Itraoperative and postoperative block characteristics as well as hemodynamic parameters were observed and recorded.
Results: Dexmedetomidine had an earlier onset and longer duration of sensory and motor block in comparison to clonidine. Sedation scores were statistically significant with dexmedetomidine group in comparison to clonidine group.
Conclusion: Dexmedetomidine was a better than clonidine as an adjuvant to levobupivacaine in epidural anaesthesia in total knee replacement.
Keywords- clonidine ,dexmedetomidine ,levobupivacaine, total knee replacement.
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