Title: Histopathological Analysis of Ovarian Tumours –Analysis of 2 Years
Author: Dr Sujeet Kumar Mandal, MD Pathology
DOI: https://dx.doi.org/10.18535/jmscr/v5i1.158
Abstract
Background: Ovarian tumours are one of the most prevalent gynaecological tumours in females . They often present in mid-decade of life insidiously. Ovarian cancer is the most frequent cause of death from gynaecological cancers.
Aims and Objectives: To study histological pattern of Ovarian Tumours in Bihar
Material and Methods: Institutional Ethical Committee approval and written informed consent from patients were taken. Ovarian specimens of 145 patients with suspected ovarian mass were studied for histopathological examination during the period of October 2012 to October 2014.
Results: Mean age of cases was 44.3 ± 9.5 years. Majority of the cases of ovarian were in age group of 20 – 40 years ( 63.45 % ) .Age rage was from 21 years to 69 years. 123 cases (84.83 % ) were benign ,3 cases (2.07 % ) were borderline and 19 cases (13.1 %) were malignant. There were 111 cases (76.55 % ) of surface tumours , 31 cases (21.38 %) germ cell, 1 case ( 0.69 % ) of sex cord , 2 cases (1.38 % ) of metastatic ovarian tumours . Among benign tumours , there were 96 cases of Serous cyst adenoma ( 66.21 % ) , 4 cases of Mature cystic Teratoma , 1 case of Serous cyst adenofibroma (0.69 % ), 1 case of Teratoma with Struma ovarii (0.69 % ) .Among malignant tumours, there were 12 cases (63.16 % ) of Serous cyst adenocarcinoma , 3 cases (15.79 % ) of Immature teratoma , 2 cases of (10.53 % ) Mucinoius cyst adenocarcinaoma, 1 case (5.26 %) of Krukenberg tumour and Granulosa cell tumour each .
Conclusion: Serous cyst adenoma are the most common benign ovarian tumour found in ovarian specimens with peak incidence at 20 – 50 years.
References
1. Morrison J. Advances in the understanding and treatment of ovarian cancer. J Br Menopause Soc, 2005; 11: 66-71.
2. Gupta N, Bisht D, Agarwal AK, Sharma VK. Retrospective and prospective study of ovarian tumors and tumor like lesions. Indian J Pathol Microbiol 2007; 50: 525-7.
3. Rieber A, Nussle K. Preoperative diagnosis of ovarian tumors with MR imaging, comparison with transvaginal sonography, positron emission tomography and histological findings. AJR Am J Roentgenol 2001; 177: 123-9.
4. Sen U, Sankaranarayanan R, Mandal S, Romana AV, Parkin DM, Siddique M. Cancer patterns in Eastern India. The first report of Kolkata Cancer Registy. Int’l J Cancer 2002; 100: 86-91
5. Layla. S.Abdulla, Nabeel S. Bondagji Histopathological pattern of ovarian neoplasms and their age distribution in the western region of Saudi Arabia, Saudi Med J 2012; Vol 33(1) 61-65.
6. Pilli GS, Suneeta KP, Dhaded AV, Yenni VV. Ovarian tumors: a study of 282 cases J Indian Med Assoc 2002; 100: 423-4.
7. S.M.TAMASKAR Ovarian sex-cord stromal tumors:”Newly Recognised Entities” Vol.2 (1), Jan.2009
8. Ahmad M, Malik TM, Afzal S, Mubarik A. Clinicopathological study of 762 ovarian neoplasms at Army Medical College Rawalpindi. Pak J Pathol 2004; 15 (4): 147-52.
9. Cook J. Family history of ovarian cancer. Current Obstetrics Gynaecology. 2002; 12:47-51
10. Sen U, Sankaranarayanan R, Mandal S, Romana AV, Parkin DM, Siddique M. Cancer patterns in Eastern India. The first report of Kolkata Cancer Registy. Int’l J Cancer 2002; 100: 86-91.
11. Vijay Kumar Bodal,TanuJindal,Manajit Singh, Rajeev Bhagat,Sarabjeetkaur, Ninder Mall, Ankit Goel and Priyanka Goyal, A clinicopathological study of ovarian lesions. Vol.13 Issue (Supplementary One) 2014.
12. Haroon S, Zia A, Idrees R, Memon A, Fatima S, Kayani N. Clinicopathological spectrum of ovarian sex cord-stromal tumors; 20 years’ retrospective study in a developing country. J Ovarian Res 2013;6:87.
13. Przybycin CG, Kurman RJ, Ronnett BM, Shih IeM, Vang R. Are all pelvic (nonuterine) serous carcinomas of tubal origin? Am J SurgPathol 2010;34:1407-16
14. La Vecchia C. Epidemiology of ovarian cancer: A summary review. Eur J Cancer Prev 2001;10:125-9.
15. Jemal A, Siegel R, Ward E, Hao Y, Xu J, Thun MJ. Cancer statistics, 2009. CA Cancer J Clin 2009;59:225-49.
16. Haroon S, Zia A, Idrees R, Memon A, Fatima S, Kayani N. Clinicopathological spectrum of ovarian sex cord-stromal tumors; 20 years’ retrospective study in a developing country. J Ovarian Res 2013;6:87.