Title: Clinical Profile, Aetiology, and Short Term Outcome of Convulsive Status Epilepticus in Children in Eastern India
Authors: Niloy Kumar Das, Baisakhi Soren, Dipankar Gupta
DOI: https://dx.doi.org/10.18535/jmscr/v5i1.109
Abstract
The study was done to assess the clinical profile, aetiology, neuroimaging pattern, short-term outcome and possible risk factors of status epilepticus (SE). A prospective study was carried out on convulsive status epilepticus patients at Pediatric Medicine Department from February 2011 to January 2012 . 40 children within age group 6 months to 12 years were included in the study. They were studied for clinical presentation, laboratory findings, efficacy of management and short-term outcome. Among 40 patients of SE aged between 6 months to 12 years, maximum (80%) were <5 yrs of age. GTCS (generalized tonic-clonic seizure) was the most common(75%) type of seizure.SE with fever was more common in <2 yrs of age (71.5%).The most common cause of SE in this study was acute symptomatic (50%) and meningitis was leading cause. Cerebral oedema (27.2%) was the most common abnormality found in neuroimaging. Seizure termination was done by Lorazepam in 60% and by diazepam and phenytoin combination in 35% patients. Age <2 years (p-value 0.04), seizure duration>45 minutes s (p 0.02) acute symptomatic etiology (p 0.04) were associated with poor outcome. We conclude that rapid termination of seizure and increase immunization coverage are important steps to prevent mortality and morbidity in SE.
Keywords: Status epilepticus, chidren, aetiology, short term outcome.
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