Title: Anaphylaxis and Human Seminal Plasma Allergy: A Review

Authors: Sukesh Krishna Chaitanya Loka*, Meghana Gubbala, Sreekar Srichurnam

 DOI:  http://dx.doi.org/10.18535/jmscr/v3i8.50

DIDS : 08.2015-XXXXXX

Abstract

Allergy can be defined as a detrimental immune-mediated hypersensitivity response to common environmental substances. The immune processes of allergy usually rely on the production of IgE antibodies specific to common allergens. Anaphylaxis is usually considered an acute, severe reaction, often with dyspnea, angioedema, and hypotension. The manifestation of allergic diseases changes throughout life: food allergies and eczema are most likely to develop in infants, asthma in young children, and rhinitis in older children and adults.  Human seminal plasma allergy is an anaphylaxis caused by immediate hypersensitivity to human seminal plasma. Immediate hypersensitivity reactions to human seminal fluid range from local swelling to generalized systemic reactions. Allergy to human seminal plasma is a rare condition and therapeutic options include the use of condoms, prescription of antihistamines and attempts at desensitization. The incidence of this allergy is higher than reported due to lack of recognition and hence early detection will enable the physician to direct an appropriate therapy. The present review focuses on clinical features, diagnosis and therapy of seminal plasma allergy.

Key words: Allergy, Anaphylaxis, Genital allergy, Human Seminal Plasma, Hypersensitivity,

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