Title: A Study of Current Outbreak of Dengue Fever in Children
Authors: Tamil Selvan, Pawan Kumar.S, Giridhar, Narayana Swamy, Mahesh Kumar
DOI: http://dx.doi.org/10.18535/jmscr/v3i8.19
DIDS : 08.2015-46187749
Background: Dengue is a major international health concern that is prevalent in tropical and sub-tropical countries. The Objective of the present study is to study the clinical profile of dengue fever in children because of lack of such research among children. Material and methods: Prospective study was conducted on all the laboratory confirmed cases of dengue fever during the outbreak of dengue fever from May 2015 to July 2015 among 300 children admitted to 4 major hospitals in Bangalore, Karnataka, India. Results: Among 300 patients studied, majority of them were males (56.6%) and in the age group of 6-10 years (36%). The most common symptoms were fever (97.3%) followed by headache( 86.6%) myalgia (86.6%),decreased appetite (83%), retroorbital pain (67.7%), abdominal pain (66.6%) and vomiting (64.3%). The most common signs were skin rash (57.3%) and hepatomegaly (14.3%). The most common complications seen were hepatic dysfunction (11%) followed by pleural effusion (3.6%) and shock (2.3%).Mortality was nil in our study. Conclusion: Clinical profile resembles with other studies but with low severity and most common complication being hepatic dysfunction. Community awareness, early diagnosis and management and vector control measures and vaccination need to be strengthened in order to reduce the increasing number of dengue cases. Keywords: Dengue fever, complications, hepatic dysfunction, shock, skin rash 1. World Health Organization; Dengue and Dengue Hemorrhagic fever. Available in www.who.int/media centre/factsheets./ fs117/en/accessed on 19.4.2013. 2. Guzmán MG, Kourí G; Dengue: An update. Lancet Infect Dis., 2002; 2: 33–42. 3. World health Organization. Dengue and dengue haemorrhagic fever. Fact Sheet.No. 117, 2002. Available from:http//www.who.int/mediacentre/factsheet s/fs117/en/. 4. Dengue in Kerala: A critical review. ICMR Bulletin. 2006;36:13–22. 5. Konar NR, Mandal AK, Saha AK. Hemorrhagic fever in Kolkata. J Assoc Physicians India. 1966;14:331–40. 6. Abdul Kader MS, Kandaswamy P, Appavoo NC, Anuradha Outbreak and control of dengue in a village of Dharmapuri, Tamil Nadu. J Commun Dis.1997;29:69–72. 7. Narayanan M, Aravind MA, Thilothammal N, Prema R, Sargunam CS, Ramamurty N. Dengue fever epidemic in Chennai-a study of clinical profile and outcome. Indian Pediatr. 2002;39:1027-33. 8. Aggarwal A, Chandra J, Aneja S, Patwari AK, Dutta AK. An epidemic of dengue hemorrhagic fever and dengue shock syndrome in children in Delhi. Indian Pediatr.1998;35:727–32. 9. Cecilia D. National Institute of Virology, Golden Jubilee Publication. Dengue Re-emerging disease 2004;4: 278–307. 10. Balaya S, Paul SD, D’Lima LV, Pavri KM. Investigations on an outbreak of dengue in Delhi in 1967. Indian J Med Res. 1969;5:767– 74. 11. Chaturvedi UC, Mathur A, Kapoor AK, Mehrotra NK, Mehrotra RM. Virological study of an epidemic of febrile illness with hemorrhagic manifestations at Kanpur, India during 1968. Bull World Health Organ. 1970;4:289–93. 12. Sulekha C, Kumar S, Philip J. Gullian-Barre syndrome following dengue fever.IndianPediatr. 2004;41:948–52. 13. Prabhakar H, Mathew P, Marshalla R, Arya M. Dengue hemorrhagic fever outbreak in October–November 1996 in Ludhiana, Punjab, India. Indian J Med Res. 1997;106:1–3. 14. Faridi M, Anju A, Kumar M, Sarafrazul A. Clinical and biochemical profile of dengue hemorrhagic fever on children in Delhi. Trop Doct. 2008;38:28–30. 15. PadibidriVS, Adhikari P, Thakare JP, Ilkal MA, Joshi GD, Pereira P, et al.The 1993 epidemic of dengue fever in Mangalore, Karnataka State, India. Southeast Asian J Trop Med Public Health. 1995;26:699–704. 16. CherianT, Ponnuraj E, Kuruvilla T, Kirubakaran C, John TJ, Raghupathy P. An epidemic of dengue hemorrhagic fever & dengue shock syndrome in and around Vellore. Indian J Med Res.1994;100:51–6. 17. Gubler DJ. Dengue and dengue hemorrhagic fever. ClinMicrobiol Rev. 1998;11:480–96. 18. Chandralekha, Gupta P, Trikha A. The north Indian dengue outbreak 2006: a retrospective analysis of intensive care units admissions in a tertiary care hospital. Trans R Soc Trop Med Hyg. 2008;102:143–7. 19. Horvath R, Mcbride WJH and Hanna JN. Clinical features of hospitalized patients during dengue 3 epidemic in Far North Queensland1997-99.Dengue Bulletin. 1999; 23: 24-29. 20. Sharma S and Sharma SK. Clinical profile of DHF in adults during 1996 outbreak in Delhi, India. Dengue Bulletin. 1998; 22: 20-27.Abstract
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