Title: Role of Mast cell in Oral lesions
Authors: Dr Isha Aggarwal, Dr Sunita Bhargava
DOI: http://dx.doi.org/10.18535/jmscr/v3i9.45
Abstract
Background: The present study was carried out for quantitative analysis of the mean MCC/optical field and MCD/sq. mm in the benign, premalignant and malignant oral lesions.
Objective: To analyse the role of mast cell in tumorogenesis.
Study Design: This study was carried out in the Department of Pathology, RNT Medical College, Udaipur. Punch biopsy of various oral lesions were selected. The sections were obtained and stained with Hematoxylin and Eosin and Toluidine blue. The number of mast cells/optical field and mast cell density/sq. mm were assessed. The following conclusions were drawn from our study.
Result: An increase in both mean MCC/optical field and MCD/sq. mm was found as the disease progress from benign to premalignant and to malignant oral lesions. This increase in the values was statistically significant between benign v/s malignant and premalignant v/s malignant. However value was found to be non-significant between benign v/s premalignant.
Keywords: Mast cells, Mast cell count, Mast cell density, Oral squamous cell carcinoma.
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