Title: Seizure Semiology and Imaging Correlation
Authors: Dilip M Rampure, Rajhounsh, Rakesh Reddy R, Swetha D
DOI: http://dx.doi.org/10.18535/jmscr/v3i10.06
Abstract
Seizure is defined as paroxysmal event due to abnormal excessive hyper synchronus discharges from an aggregate of CNS neurons. Although variety of factors influence the incidence and prevalence of seizure, approximately 5-10% of population will have at least one seizure during their lifetime. This study is done to evaluate etiology of seizures, identification and localization of intracranial pathologies and correlation with CT scan. In our study58% had generalized seizures and 42% had partial seizures. Overall CT scan was abnormal in 48% of patients, 37.5% of generalized seizure group and 62.5% of partial seizure group patients. Majority of cases of generalized seizures were idiopathic.• Tuberculoma was the most common cause of partial seizure. With a reliable history and clinical examination, if proper analysis of etiology is made with available investigations, the epilepsy can be treated accordingly, thus reducing the morbidity and mortality associated with it.
References
1. Mussico M, Beghi E, Solari A: Treatment of first tonic-clonic seizure does notimptrove the prognosis of epilepsy. First seizure trail group (FIRST group):Neurology 1997;Oct49 (4): 991-8.
2. Van Donselaar CA, Schimsheimer RJ, Geerts AT: Value of the electroencephalogram in adult patients with untreated ldeopathic firstseizures: Arch Neural 2000 Mar; 49(3); 231-7.
3. Hopkins A, Garman A, Clarke C: The first seizure in adult life. Value ofclinical features, electroencephalography and computed tomographicscanning in prediction of seizure recurrence. Lancet 1998 Apr.2, 1 (8588):721-6.
4. J. AnnegersJf, Shirts SB, Hauser WA: Risk of recurrence after an initialunprovoked seizure. Epilepsia 1996 Jan-Feb; 27(1): 43-50.
5. Bora I, Seckin B, Zarifoglu M: Risk of recurrence after first unprovoked tonic-clonic seizure in adults. Neuro11995; 242: 157-163.
6. Shinnar S, Berg AT, Moshe SL, O'Dell C, Alemany M, Newstein D, et al. Therisk of seizure recurrence after a first unprovoked afebrile seizure inchildhood: an extended follow-up. Pediatrics 1996;98(2 pt 1):216-25.
7. Wallace J.C.: Radionuc1ide brain scanning in investigation of late onsetseizures. The Lancet: Sat, Dec.21, 1974.
8. Scollo-Lavizzari G, Eichhorin K, Wuthrich R: Computerised Transaxial Tomography in the diagnosis of Epilepsy. EurNeurol 15: 5-8; 1977.
9. Granieri E, Rosati G, Tola R, Pavoni M, Paolino E, Pinna L, Moneti VC. A descriptive study of epilepsy in the district of copparo, Italy, 1964-1978. Epilepsia 1983;24(4):502-514.
10. pradeep PV , Balasubramanian R, Rao SN. Clinical profile and etiological analysis of late onset epilepsy. JAPI 2003;51 : 1192
11. perez Lopez JL, Longo J et al. Late onset epileptic seizures- A retrospective study of 250 patients. Acta Neurologica Scandinayica: 1985;72(4):380-4
12. Ahuja, G.K, Mohanta, A (1982) Late onset epilepsy Acta Neurologica Scandinayica 66, 216-266