Title: Effects of Intraperitoneal Instillation of Local Anesthetic Agents in Laparoscopic Cholecystectomy –A Clinical Comparison Between 0.5% Lignocaine, 0.2% Ropivacaine & 0.125%Bupivacaine
Authors: Pacharla Indira, Rajola Raghu, Anepu Kiran Kumar
DOI: http://dx.doi.org/10.18535/jmscr/v4i1.22
Abstract
Introduction: Minimal access surgery offers advantages to patients in terms of reduced peri-operative morbidity andshortened recovery times.
Objective:To compare the effects of intraperitoneal instillation of lignocaine, bupivacaine and ropivacaine in patients undergoing laparoscopic cholecystectomy.
Material and Methods: 75 adult patients of ASA physical status I and II in the age group of 20 – 55 yrs were enrolled in the study and divided into 3 groups of 25 each .Group L :20 ml of 0.5% Lignocaine, Group B: 20 ml of 0.125% Bupivacaine , Group R : 20 ml of 0.2% Ropivacaine respectively were instilled intraperitoneally before CO2 Insufflation .
Results: Age and sex distribution in all the groups were similar. Heart rate, Systolic & Diastolic Blood pressure, Mean arterial blood pressure and mean trend of SpO2 in all the groups remained similar over the periods. The mean visual analog score in all groups varied considerably within (between time) and between the groups (treatment) especially comparatively higher in Group L at initial hours 15 min to 30 min and at end hours 12-24 hrs as compared to Group B. On an average, the frequency of dosing and mean no. of rescue analgesic doses were higher in Group L, B than R.
Conclusion: We conclude that intraperitoneal instillation of local anaesthetic is an easy, cheap, and reliable method of providing good perioperative analgesia and hemodynamic stability in laparoscopic cholecystectomy .
Keywords:Bupivacaine, Intraperitoneal Local Anaesthetic , Laparoscopic cholecystectomy,. Lignocaine, Ropivacaine.
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